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Clinicians really should choose treatment to inject testosterone undecanoate deeply into the gluteal muscle and stop intravascular injection. Together with POME reactions, instances of anaphylaxis, which includes most likely lethal gatherings, have also been documented soon after testosterone undecanoate injection intramuscularly. It isn't a good idea to offer testosterone undecanoate again to patients who might have skilled hypersensitive responses. Watch the affected person for half an hour next each administration, and in the occasion of serious POME or anaphylactoid reactions, administer the necessary professional medical care.[1]
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Testosterone can improve the anticoagulant motion of warfarin.[18] Really serious bleeding has actually been reported in some sufferers using this type of drug-drug interaction. Even though the mechanism is unclear, testosterone may perhaps cut down procoagulant aspects. Reduction of warfarin dosage may very well be required if testosterone therapy is coadministered.
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On this page, we make use of the term “male” to confer with a person’s sexual intercourse assigned at start. For information regarding the distinction between sex and gender, see this informative article.